Abstract

Introduction

Passage of legislation in Washington, Colorado, Oregon, Alaska, and the District of Columbia allowing recreational use of marijuana, despite federal regulation to the contrary, highlights the continued debate surrounding this unconventional plant. Allergies to marijuana are not commonly reported in the medical literature despite being the most widely used illicit drug in the world. However, especially in the setting of an evolving legal status, marijuana might become an increasingly relevant “weed” for the allergist. This article aims to review the literature pertaining to Cannabis sativa in the context of allergic disease and its potential clinical implications.