Cannabis & The COVID-19 Pandemic: A Physician’s Perspective
Joe D. Goldstrich, MD, FACC outlines what we know about the antiviral properties of cannabis and whether or not it could be helpful or detrimental for COVID-19.
Archive for month: March, 2020
Terpenoids From Cannabis Do Not Mediate an Entourage Effect by Acting at Cannabinoid Receptors
Frontiers in Pharmacology, 25 March 2020
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The entourage effect was a proposed explanation for biological observations that endocannabinoid ligand activities can be modified by other lipids released from cells at the same time. An increasing volume of anecdotal reports and interest in the plant have provoked research i…
Role of cannabis in inflammatory bowel diseases.
Annals of Gastroenterology, March-April 2020
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For many centuries, cannabis (marijuana) has been used for both recreational and medicinal purposes. Currently, there are about 192 million cannabis users worldwide, constituting approximately 3.9% of the global population. Cannabis comprises more than 70 aromatic hydrocarbon …
The Effect of Piperine on Oral Absorption of Cannabidiol following Acute vs. Chronic Administration.
European Journal of Pharmaceutical Sciences, 17 March 2020
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The piperine is an alkaloid naturally found mostly in black pepper with a myriad of pharmacological attributes. The most far reaching indication of piperine is its use as an absorption enhancer, with supportive data regarding piperine’s ability to inhibit first pass effect mec…
Sex, Intimacy, and Cannabis
Sarah Mann, MD separates myth and conjecture from what is known (and unknown) about cannabis and sex.
Labeling of Cannabidiol Products: A Public Health Perspective
Cannabis and Cannabinoid Research, 6 March 2020
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Introduction: Interest in the therapeutic use of cannabidiol (CBD) has reached a fever-pitch in recent months, as CBD-containing products appear everywhere from online retailers to grocery stores and gas stations. The widespread availability of hemp-derived CBD products is con…
Phytocannabinoids: Useful Drugs for the Treatment of Obesity? Special Focus on Cannabidiol.
Frontiers in Endocrinology, 4 March 2020
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Currently, an increasing number of diseases related to insulin resistance and obesity is an alarming problem worldwide. It is well-known that the above states can lead to the development of type 2 diabetes, hypertension, and cardiovascular diseases. An excessive amount of tria…
The Endocannabinoid System of Animals
This review paper by Dr. Robert Silver gives an overview of the ECS in animals and highlights it as a topic of interest for emerging therapeutics.
Drug interactions with cannabinoids.
CMAJ : Canadian Medical Association journal, 2 March 2020
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Cannabinoid levels can be increased by other medications. Cannabinoids can affect levels of other drugs. Smoking marijuana can increase clearance of some drugs. Additive effects can occur with other drugs. There are potential “red flag” interactions.
Cannabis education needs assessment among Canadian physicians-in-training.
Canadian researchers found that the average training from physicians in training was 25% less than what they desired and that further training was paramount for them to engage in cannabis for therapeutic purposes (2020).
The influence cannabidiol on delayed onset of muscle soreness
CBD appears to have a significant influence on muscle soreness associated with exercise induced muscle damage and delayed onset of muscle soreness when consumed immediately after strenuous exercise.