Plasma anandamide concentrations are lower in children with autism spectrum disorder.

Authors: Debra S. Karhson, Karolina M. Krasinska, Jamie Ahloy Dallaire, et al
Molecular Autism, 12 March 2018

BACKGROUND: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by restricted, stereotyped behaviors and impairments in social communication. Although the underlying biological mechanisms of ASD remain poorly understood, recent preclinical research ha…

Endocannabinoid Signaling in Autism.

Authors: Bhismadev Chakrabarti, Antonio Persico, Natalia Battista, Mauro Maccarrone
Neurotherapeutics, October 2015

Autism spectrum disorder (ASD) is a complex behavioral condition with onset during early childhood and a lifelong course in the vast majority of cases. To date, no behavioral, genetic, brain imaging, or electrophysiological test can specifically validate a clinical diagnosis o…

Cannabinoid receptor type 2, but not type 1, is up-regulated in peripheral blood mononuclear cells of children affected by autistic disorders.

Authors: Dario Siniscalco, Anna Sapone, Catia Giordano, Alessandra Cirillo, Laura de Magistris, et al
Journal of Autism and Developmental Disorders, November 2013

Autistic disorders (ADs) are heterogeneous neurodevelopmental disorders arised by the interaction of genes and environmental factors. Dysfunctions in social interaction and communication skills, repetitive and stereotypic verbal and non-verbal behaviours are common features of…

Would some cannabinoids ameliorate symptoms of autism?

Authors: Rami Bou Khalil
European Child & Adolescent Psychiatry, DATE

Dear Sir, There has been a massive growth of public awareness and research funding around autism spectrum disorders (ASD) over the past 10 years. This disorder is one of the groups of neurodevelopmental disorders known as pervasive developmental disorders characterized by thre…

Use of dronabinol (delta-9-THC) in autism: A prospective single-case-study with an early infantile autistic child.

Authors: René Kurz, Kurt Blaas
Cannabinoids, 21 November 2010

Objective: To evaluate the effectiveness of dronabinol (delta-9-THC) as supplementary therapy in a child with autistic disorder. Methods: A child who met the DSM-IV (Diagnostic and Statistical Manual of Mental Disorders) criteria for a diagnosis of autistic disorder and who to…