Use of cannabinoids in cancer patients: A Society of Gynecologic Oncology (SGO) clinical practice statement.

Authors: B. Whitcomb, C. Lutman, M. Pearl, E. Medlin, E. Prendergast, K. Robison, W. Burke
Gynecologic Oncology, 10 January 2020

Tetrahydrocannabinol (THC), cannabidiol (CBD) and cannabinol (CBN) affect the human endocannabinoid system. Cannabinoids reduce chemotherapy induced nausea or vomiting (CINV) and neuropathic pain. Each state has its own regulations for medical and recreational cannabis use. Ef…

Medical students are unprepared to counsel patients about medical cannabis and want to learn more.

Authors: Abraham Benavides, Nicholas Gregorio, Puneet Gupta, Mikhail Kogan
Complementary Therapies in Medicine, January 2020

Introduction: Over-the-counter and prescribed medical cannabis products are used by patients for various conditions including psychiatric disorders, pain management, and other neurodegenerative conditions.1 Despite this growing public interest and increasing legal availability…

Cannabinoids and the expanded endocannabinoid system in neurological disorders.

Authors: Luigia Cristino, Tiziana Bisogno, Vincenzo Di Marzo
Nature Reviews Neurology, January 2020

Anecdotal evidence that cannabis preparations have medical benefits together with the discovery of the psychotropic plant cannabinoid Δ9-tetrahydrocannabinol (THC) initiated efforts to develop cannabinoid-based therapeutics. These efforts have been marked by disappointment, es…

Cannabis consumption and non-alcoholic fatty liver disease. A three years longitudinal study in first episode non-affective psychosis patients.

Authors: Javier Vázquez-Bourgon, Víctor Ortiz-García de la Foz, Irene Suarez-Pereira, et al
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 20 December 2019

INTRODUCTION: Increased incidence of obesity and excess weight lead to an increased incidence of non-alcoholic fatty liver disease (NAFLD). Recent evidence indicates a protective effect of cannabis consumption on weight gain and related metabolic alterations in psychosis patie…

IACM 2019 Highlights: Defending Doctors’ Rights Across the Globe

The 2019 IACM conference in Berlin highlighted talks from the top professionals in the field of cannabis science. Christine Milentis reports on the history of cannabis for medical use and the rights of doctors across the globe to prescribe it.

Indications and administration practices amongst medical cannabis healthcare providers: a cross-sectional survey.

A study published in BMC Family Practice sought to characterize the clinical practice characteristics of medical professionals who recommend cannabis.

Changing My Specialty

Dr. Sarah Mann tells the tale of one of her patients who inspired the shift towards a cannabis integrated practice.

The Effectiveness of Topical Cannabidiol Oil in Symptomatic Relief of Peripheral Neuropathy of the Lower Extremities.

Authors: Dixon H. Xu, Benjamin D. Cullen, Meng Tang, Yujiang Fang
Current Pharmaceutical Biotechnology, December 2019

BACKGROUND: Peripheral neuropathy can significantly impact the quality of life for those who are affected, as therapies from the current treatment algorithm often fail to deliver adequate symptom relief. There has, however, been an increasing body of evidence for the use of ca…

The Potential Benefits of Palmitoylethanolamide in Palliation: A Qualitative Systematic Review.

Authors: Mellar P. Davis, Bertrand Behm, Zankhana Mehta, Carlos Fernandez
American Journal of Hospice and Palliative Medicine, December 2019

Palmitoylethanolamide (PEA) is a nutraceutical endocannabinoid that was retrospectively discovered in egg yolks. Feeding poor children with known streptococcal infections prevented rheumatic fever. Subsequently, it was found to alter the course of influenza. Unfortunately, the…

The Endocannabinoid System in Pediatric Inflammatory and Immune Diseases.

Authors: Maura Argenziano, Chiara Tortora, Giulia Bellini, Alessandra Di Paola, Francesca Punzo, et al
International Journal of Molecular Sciences, 23 November 2019

Endocannabinoid system consists of cannabinoid type 1 (CB1) and cannabinoid type 2 (CB2) receptors, their endogenous ligands, and the enzymes responsible for their synthesis and degradation. CB2, to a great extent, and CB1, to a lesser extent, are involved in regulating the im…

Education, Knowledge, and Practice Characteristics of Cannabis Physicians

Kevin M. Takakuwa, MD and Dr. Dustin Sulak evaluate how US medical professionals received their cannabis medicine training in Mary Ann Liebert, Inc.

The Role of the Endocannabinoid System in Aetiopathogenesis of Endometriosis: A Potential Therapeutic Target

Authors: Keisuke Tanaka, Leah Mayne, Akram Khalil, David Baartz, Lars Eriksson, Sally-Anne Mortlock, et al
European Journal of Obstetrics & Gynecology and Reproductive Biology, 15 November 2019

Endometriosis affects a large proportion of women during their reproductive years and is associated with pain and infertility, also affecting psychological wellbeing and quality of life. The pathogenesis of the disease remains unclear, although it is believed to be multifactor…