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Use of Cannabidiol in the Treatment of Epilepsy: Efficacy and Security in Clinical Trials.
Authors: Serena Silvestro, Santa Mammana, Eugenio Cavalli, Placido Bramanti, Emanuela Mazzon
Molecules, April 2019
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Cannabidiol (CBD) is one of the cannabinoids with non-psychotropic action, extracted from Cannabis sativa. CBD is a terpenophenol and it has received a great scientific interest thanks to its medical applications. This compound showed efficacy as anti-seizure, antipsychotic, n…
You Must Remember This (Re: Mushrooms)
Eating mushrooms may reduce the risk of cognitive impairment, according to a study published in the Journal of Alzheimer’s Disease.
Practical Perspectives in the Treatment of Nausea and Vomiting.
Authors: David J. Cangemi, Braden Kuo
Journal of Clinical Gastroenterology, March 2019
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Nausea and vomiting result from complex interactions between afferent and efferent pathways of the gastrointestinal tract, central nervous system, and autonomic nervous system. Afferent pathways from the vagus nerve, vestibular system, and chemoreceptor trigger zone project to…
Targeting the Endocannabinoid System in Psychiatric Illness.
Prevalence of psychiatric disorders continues to rise globally, yet remission rates and patient outcome remain less than ideal. As a result, novel treatment approaches for these disorders are necessary to decrease societal economic burden, as well as increase individual functi…
Women’s perspectives about cannabis use during pregnancy and the postpartum period: An integrative review.
Authors: Hamideh Bayrampour, Mike Zahradnik, Sarka Lisonkova, Patti Janssen
Preventive Medicine, February 2019
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Cannabis is the most commonly used illicit drug among general and pregnant populations. Despite recommendations to abstain from cannabis use, its use is increasing during the perinatal period. In this integrative review, we aim to understand women’s perspectives about the heal…
The endocannabinoid system and stroke: A focused review.
Authors: Bradley Kolb, Hamidreza Saber, Hassan Fadel, Gary Rajah
Brain Circulation, January-March 2019
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Stroke is an important cause of morbidity and mortality worldwide. Development of novel neuroprotectants is of paramount importance. This review seeks to summarize the recent evidence for the role of the endocannabinoid signaling system in stroke pathophysiology, as well as th…
Potential Use of Cannabinoids for the Treatment of Pancreatic Cancer.
Authors: Golnaz Sharafi, Hong He, Mehrdad Nikfarjam
Journal of Pancreatic Cancer, 25 January 2019
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Background: Cannabinoid extracts may have anticancer properties, which can improve cancer treatment outcomes. The aim of this review is to determine the potentially utility of cannabinoids in the treatment of pancreatic cancer. Methods: A literature review focused on the biolo…
Therapeutic potential of cannabinoids as neuroprotective agents for damaged cells conducing to movement disorders.
Authors: Mario Antonazzo, María Botta, Harkaitz Bengoetxea, José Ángel Ruiz-Ortega, Teresa Morera-Herreras
International Review of Neurobiology, 2019
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The basal ganglia (BG), an organized network of nuclei that integrates cortical information, play a crucial role in controlling motor function. In fact, movement disorders such as Parkinson’s disease (PD) and Huntington’s disease (HD) are caused by the degeneration of specific…
A hunger for hunger: a review of palliative therapies for cancer-associated anorexia.
Authors: Daniel S. Childs, Aminah Jatoi
Annals of Palliative Medicine, January 2019
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Cancer-associated anorexia, or loss of appetite, is prevalent, distressing to patients and their families, and associated with poorer outcomes in patients with advanced cancer. A well-defined therapeutic strategy remains to be defined. We present here a review of appetite loss…
Patient Counseling Guidelines for the Use of Cannabis for the Treatment of Chemotherapy-Induced Nausea/Vomiting and Chronic Pain.
Authors: Patrick Makary, Jayesh R. Parmar, Natalie Mims, Nile M. Khanfar, Robert A. Freeman
Journal of Pain and Palliative Care Pharmacotherapy, December 2018
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The use of cannabis medications has grown in recent years for the symptomatic relief of chemotherapy-induced nausea/vomiting (CINV) and chronic pain (cancer-related and non-cancer-related). As states legalize the use of cannabis, it is important for pharmacists and other healt…
Endocannabinoids, exercise, pain, and a path to health with aging.
Authors: Bruce A.Watkins
Molecular Aspects of Medicine, December 2018
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Physical activity is an important lifestyle factor for growth, development, and sustained health throughout life. In recent years, the benefits of physical activity have drawn more attention to its physiological effects on the body, including well-being. The endocannabinoid sy…
Cannabinoids in depressive disorders.
Authors: Ewa Poleszak, Sylwia Wośko, Karolina Sławińska, Aleksandra Szopa, Andrzej Wróbel, Anna Serefko
Life Sciences, 15 November 2018
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Cannabis sativa is one of the most popular recreational and medicinal plants. Benefits from use of cannabinoid agents in epilepsy, multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, and others have been suggested. It seems that the endocannabinoid system is also inv…