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Cannabinoid exposure in adolescent female rats induces transgenerational effects on morphine conditioned place preference in male offspring.

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Authors: John J Byrnes, Nicole L Johnson, Marian E Schenk, Elizabeth M Byrnes
Journal of Psychopharmacology, October 2012
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In the United States, marijuana is one of the drugs most abused by adolescents, with females representing a growing number of users. In previous studies, treatment of adolescent female rats with morphine significantly altered brain reward systems in future offspring. As both c…

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The endocannabinoid-CB receptor system: Importance for development and in pediatric disease.

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Authors: Ester Fride
Neuro endocrinology letters, February-April 2004
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Endogenous cannabinoids (endocannabinoids) and their cannabinoid CB1 and CB2 receptors, are present from the early stages of gestation and play a number of vital roles for the developing organism. Although most of these data are collected from animal studies, a role for cannab…

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