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The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities

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The newly discovered endocannabinoid system (ECS; comprising the endogenous lipid mediators endocanna- binoids present in virtually all tissues, their G-protein- coupled cannabinoid receptors, biosynthetic pathways and metabolizing enzymes) has been implicated in multiple regulatory functions both in health and disease.

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Cannabinoid receptor type 1 and 2 expression in the skin of healthy dogs and dogs with atopic dermatitis.

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Authors: Luca Campora, Vincenzo Miragliotta, Emanuele Ricci, Luigia Cristino, Vincenzo Di Marzo, et al
American Journal of Veterinary Research, July 2012
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OBJECTIVE: To determine the distribution of cannabinoid receptor type 1 (CB1) and cannabinoid receptor type 2 (CB2) in skin (including hair follicles and sweat and sebaceous glands) of clinically normal dogs and dogs with atopic dermatitis (AD) and to compare results with thos…

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