Authors: Tangui Barré, Marie Libérée Nishimwe, Camelia Protopopescu, Fabienne Marcellin, Fabrice Carrat, Céline Dorival, Elisabeth Delarocque‐Astagneau, Dominique Larrey, Marc Bourlière, Ventzislava Petrov‐Sanchez, Mélanie Simony, Stanislas Pol, Hélène Fontaine, Patrizia Carrieri…
International Journal of Molecular Sciences, 29 April 2019
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Endogenous cannabinoids (ECs) are lipid-signaling molecules that specifically bind to cannabinoid receptor types 1 and 2 (CB1R and CB2R) and are highly expressed in central and many peripheral tissues under pathological conditions. Activation of hepatic CB1R is associated with…
Seminars in Immunopathology, June 2009
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Endocannabinoids are endogenous bioactive lipid mediators present both in the brain and various peripheral tissues, which exert their biological effects via interaction with specific G-protein-coupled cannabinoid receptors, the CB(1) and CB(2). Pathological overactivation of t…