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Inhibition of basal and ultraviolet B-induced melanogenesis by cannabinoid CB(1) receptors: a keratinocyte-dependent effect.

Authors: Sofia Magina, Carina Esteves-Pinto, Eduardo Moura, Maria Paula Serrão, et al
Archives of Dermatological Research, April 2011

Ultraviolet radiation is the major environmental insult to the skin and stimulates the synthesis of melanin in melanocytes, which then distribute it to the neighboring keratinocytes where it confers photo-protection. Skin color results from the paracrine interaction between th…